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Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis
Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear. In this study, we investigated the origin and contribution of endogenous histamine to AMI. Histidine decarboxylase (HDC) is the unique enzy...
Autores principales: | Deng, Long, Hong, Tao, Lin, Jinyi, Ding, Suling, Huang, Zheyong, Chen, Jinmiao, Jia, Jianguo, Zou, Yunzeng, Wang, Timothy C., Yang, Xiangdong, Ge, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642534/ https://www.ncbi.nlm.nih.gov/pubmed/26278136 http://dx.doi.org/10.1038/srep13131 |
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