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TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability

Induced pluripotent stem cells (iPSCs) have revolutionized the world of regenerative medicine; nevertheless, the exact molecular mechanisms underlying their generation and differentiation remain elusive. Here, we investigated the role of the cell fate determinant TRIM32 in modulating such processes....

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Detalles Bibliográficos
Autores principales: Bahnassawy, Lamia’a, Perumal, Thanneer M., Gonzalez-Cano, Laura, Hillje, Anna-Lena, Taher, Leila, Makalowski, Wojciech, Suzuki, Yutaka, Fuellen, Georg, Sol, Antonio del, Schwamborn, Jens Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642535/
https://www.ncbi.nlm.nih.gov/pubmed/26307407
http://dx.doi.org/10.1038/srep13456