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TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
Induced pluripotent stem cells (iPSCs) have revolutionized the world of regenerative medicine; nevertheless, the exact molecular mechanisms underlying their generation and differentiation remain elusive. Here, we investigated the role of the cell fate determinant TRIM32 in modulating such processes....
Autores principales: | Bahnassawy, Lamia’a, Perumal, Thanneer M., Gonzalez-Cano, Laura, Hillje, Anna-Lena, Taher, Leila, Makalowski, Wojciech, Suzuki, Yutaka, Fuellen, Georg, Sol, Antonio del, Schwamborn, Jens Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642535/ https://www.ncbi.nlm.nih.gov/pubmed/26307407 http://dx.doi.org/10.1038/srep13456 |
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