IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway

Myeloid-derived suppressor cells (MDSCs) are immune negative regulators in the tumour microenvironment. Interleukin (IL)-11, a member of IL-6 family cytokines, functions through the unique receptor IL-11 receptor α coupled with the common signal transducer gp130. IL-11-gp130 signalling causes activa...

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Detalles Bibliográficos
Autores principales: Sumida, Kentaro, Ohno, Yosuke, Ohtake, Junya, Kaneumi, Shun, Kishikawa, Takuto, Takahashi, Norihiko, Taketomi, Akinobu, Kitamura, Hidemitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642551/
https://www.ncbi.nlm.nih.gov/pubmed/28781374
http://dx.doi.org/10.1038/srep13650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642551/
https://www.ncbi.nlm.nih.gov/pubmed/28781374
http://dx.doi.org/10.1038/srep13650

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