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One, two or three? Probing the stoichiometry of membrane proteins by single-molecule localization microscopy
Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642553/ https://www.ncbi.nlm.nih.gov/pubmed/26358640 http://dx.doi.org/10.1038/srep14072 |