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Clinicopathological Significance of CDKN2A Promoter Hypermethylation Frequency with Pancreatic Cancer
The prognosis of pancreatic cancer patients is very poor, with a 5-year survival of less than 6%. Previous studies demonstrated that the loss of function of CDKN2A is mainly caused by the hypermethylation of CDKN2A gene promoter; however, whether or not it is associated with the incidence of pancrea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642558/ https://www.ncbi.nlm.nih.gov/pubmed/26338139 http://dx.doi.org/10.1038/srep13563 |