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Clinicopathological Significance of CDKN2A Promoter Hypermethylation Frequency with Pancreatic Cancer

The prognosis of pancreatic cancer patients is very poor, with a 5-year survival of less than 6%. Previous studies demonstrated that the loss of function of CDKN2A is mainly caused by the hypermethylation of CDKN2A gene promoter; however, whether or not it is associated with the incidence of pancrea...

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Detalles Bibliográficos
Autores principales: Tang, Bo, Li, Yang, Qi, Guangying, Yuan, Shengguang, Wang, Zhenran, Yu, Shuiping, Li, Bo, He, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642558/
https://www.ncbi.nlm.nih.gov/pubmed/26338139
http://dx.doi.org/10.1038/srep13563