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High resolution 4D HPCH experiment for sequential assignment of (13)C-labeled RNAs via phosphodiester backbone
The three-dimensional structure determination of RNAs by NMR spectroscopy requires sequential resonance assignment, often hampered by assignment ambiguities and limited dispersion of (1)H and (13)C chemical shifts, especially of C4′/H4′. Here we present a novel through-bond 4D HPCH NMR experiment in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642592/ https://www.ncbi.nlm.nih.gov/pubmed/26409925 http://dx.doi.org/10.1007/s10858-015-9989-5 |