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Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery
BACKGROUND: Microbial infections have been implicated in initiating and enhancing severity of autoimmune diseases including the demyelinating disease multiple sclerosis (MS). Nevertheless, the incidence of both acute and persisting viral infections without evidence of autoimmune sequelae suggests th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642610/ https://www.ncbi.nlm.nih.gov/pubmed/26559484 http://dx.doi.org/10.1186/s12974-015-0426-1 |