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Central memory CD4+ T cells are preferential targets of double infection by HIV-1

BACKGROUND: Template switching between two distinct HIV-1 RNA genomes during reverse transcription gives rise to recombinant viruses that greatly expand the genetic diversity of HIV-1 and have adverse implications for drug resistance, immune escape, and vaccine design. Virions with two distinct geno...

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Detalles Bibliográficos
Autores principales: Haqqani, Aiman A., Marek, Samantha L., Kumar, Jagadish, Davenport, Miles, Wang, Heng, Tilton, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642630/
https://www.ncbi.nlm.nih.gov/pubmed/26559763
http://dx.doi.org/10.1186/s12985-015-0415-0