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Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamine

Glutamate receptors sensitive to N-methyl-d-aspartate (NMDA) are involved in embryonic brain development but their activity may be modulated by the kynurenine pathway of tryptophan metabolism which includes an agonist (quinolinic acid) and an antagonist (kynurenic acid) at these receptors. Our previ...

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Detalles Bibliográficos
Autores principales: Forrest, C.M., McNair, K., Pisar, M., Khalil, O.S., Darlington, L.G., Stone, T.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642643/
https://www.ncbi.nlm.nih.gov/pubmed/26365611
http://dx.doi.org/10.1016/j.neuroscience.2015.09.022