Cargando…

Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer’s disease lacking functional B and T cells

INTRODUCTION: In Alzheimer’s disease, accumulation and pathological aggregation of amyloid β-peptide is accompanied by the induction of complex immune responses, which have been attributed both beneficial and detrimental properties. Such responses implicate various cell types of the innate and adapt...

Descripción completa

Detalles Bibliográficos
Autores principales: Späni, Claudia, Suter, Tobias, Derungs, Rebecca, Ferretti, Maria Teresa, Welt, Tobias, Wirth, Fabian, Gericke, Christoph, Nitsch, Roger M., Kulic, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642668/
https://www.ncbi.nlm.nih.gov/pubmed/26558367
http://dx.doi.org/10.1186/s40478-015-0251-x