An investigation of causes of false positive single nucleotide polymorphisms using simulated reads from a small eukaryote genome

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are widely used molecular markers, and their use has increased massively since the inception of Next Generation Sequencing (NGS) technologies, which allow detection of large numbers of SNPs at low cost. However, both NGS data and their analysis are...

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Detalles Bibliográficos
Autores principales: Ribeiro, Antonio, Golicz, Agnieszka, Hackett, Christine Anne, Milne, Iain, Stephen, Gordon, Marshall, David, Flavell, Andrew J., Bayer, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642669/
https://www.ncbi.nlm.nih.gov/pubmed/26558718
http://dx.doi.org/10.1186/s12859-015-0801-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642669/
https://www.ncbi.nlm.nih.gov/pubmed/26558718
http://dx.doi.org/10.1186/s12859-015-0801-z

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