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Reprogramming barriers and enhancers: strategies to enhance the efficiency and kinetics of induced pluripotency
Induced pluripotent stem cells are powerful tools for disease modeling, drug screening, and cell transplantation therapies. These cells can be generated directly from somatic cells by ectopic expression of defined factors through a reprogramming process. However, pluripotent reprogramming is an inef...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642739/ https://www.ncbi.nlm.nih.gov/pubmed/26566431 http://dx.doi.org/10.1186/s13619-015-0024-9 |