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Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats

Aging increases oxidative stress and inflammation. Melatonin counteracts inflammation and apoptosis. This study investigated the possible protective effect of melatonin on the inflammatory and apoptotic response secondary to ischemia induced by blockade of the right middle cerebral artery (MCA) in a...

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Detalles Bibliográficos
Autores principales: Paredes, Sergio D., Rancan, Lisa, Kireev, Roman, González, Alberto, Louzao, Pedro, González, Pablo, Rodríguez-Bobada, Cruz, García, Cruz, Vara, Elena, Tresguerres, Jesús A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830/
https://www.ncbi.nlm.nih.gov/pubmed/26594596
http://dx.doi.org/10.1089/biores.2015.0032