Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics

The apicomplexan, Cryptosporidium parvum, possesses a bacterial-type lactate dehydrogenase (CpLDH). This is considered to be an essential enzyme, as this parasite lacks the Krebs cycle and cytochrome-based respiration, and mainly–if not solely, relies on glycolysis to produce ATP. Here, we provide e...

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Detalles Bibliográficos
Autores principales: Zhang, Haili, Guo, Fengguang, Zhu, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642935/
https://www.ncbi.nlm.nih.gov/pubmed/26562790
http://dx.doi.org/10.1371/journal.ppat.1005250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642935/
https://www.ncbi.nlm.nih.gov/pubmed/26562790
http://dx.doi.org/10.1371/journal.ppat.1005250

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