Identification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest Models

Cancer genomes contain vast amounts of somatic mutations, many of which are passenger mutations not involved in oncogenesis. Whereas driver mutations in protein-coding genes can be distinguished from passenger mutations based on their recurrence, non-coding mutations are usually not recurrent at the...

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Detalles Bibliográficos
Autores principales: Svetlichnyy, Dmitry, Imrichova, Hana, Fiers, Mark, Kalender Atak, Zeynep, Aerts, Stein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642938/
https://www.ncbi.nlm.nih.gov/pubmed/26562774
http://dx.doi.org/10.1371/journal.pcbi.1004590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642938/
https://www.ncbi.nlm.nih.gov/pubmed/26562774
http://dx.doi.org/10.1371/journal.pcbi.1004590

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