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Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia

BACKGROUND: ROR1 is a receptor tyrosine kinase expressed in chronic lymphocytic leukemia (CLL) and several other malignancies but absent in most adult normal tissues. ROR1 is considered an onco-fetal antigen. In the present study we analysed spontaneous humoral and cellular immunity against ROR1 in...

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Detalles Bibliográficos
Autores principales: Hojjat-Farsangi, Mohammad, Jeddi-Tehrani, Mahmood, Daneshmanesh, Amir Hossein, Mozaffari, Fariba, Moshfegh, Ali, Hansson, Lotta, Razavi, Seyed Mohsen, Sharifian, Ramazan Ali, Rabbani, Hodjattallah, Österborg, Anders, Mellstedt, Håkan, Shokri, Fazel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642968/
https://www.ncbi.nlm.nih.gov/pubmed/26562161
http://dx.doi.org/10.1371/journal.pone.0142310