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Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles

The centrosome-associated C1orf96/Centriole, Cilia and Spindle-Associated Protein (CSAP) targets polyglutamylated tubulin in mitotic microtubules (MTs). Loss of CSAP causes critical defects in brain development; however, it is unclear how CSAP association with MTs affects mitosis progression. In thi...

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Detalles Bibliográficos
Autores principales: Ohta, Shinya, Hamada, Mayako, Sato, Nobuko, Toramoto, Iyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642972/
https://www.ncbi.nlm.nih.gov/pubmed/26562023
http://dx.doi.org/10.1371/journal.pone.0142798