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Advanced Glycation End Products Impair Voltage-Gated K+ Channels-Mediated Coronary Vasodilation in Diabetic Rats
BACKGROUND: We have previously reported that high glucose impairs coronary vasodilation by reducing voltage-gated K(+) (K(v)) channel activity. However, the underlying mechanisms remain unknown. Advanced glycation end products (AGEs) are potent factors that contribute to the development of diabetic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642979/ https://www.ncbi.nlm.nih.gov/pubmed/26562843 http://dx.doi.org/10.1371/journal.pone.0142865 |