Cargando…

Advanced Glycation End Products Impair Voltage-Gated K+ Channels-Mediated Coronary Vasodilation in Diabetic Rats

BACKGROUND: We have previously reported that high glucose impairs coronary vasodilation by reducing voltage-gated K(+) (K(v)) channel activity. However, the underlying mechanisms remain unknown. Advanced glycation end products (AGEs) are potent factors that contribute to the development of diabetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Wen, Li, Weiping, Chen, Hui, Liu, Huirong, Huang, Haixia, Li, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642979/
https://www.ncbi.nlm.nih.gov/pubmed/26562843
http://dx.doi.org/10.1371/journal.pone.0142865