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Physical Characterization of Gemini Surfactant-Based Synthetic Vectors for the Delivery of Linear Covalently Closed (LCC) DNA Ministrings

In combination with novel linear covalently closed (LCC) DNA minivectors, referred to as DNA ministrings, a gemini surfactant-based synthetic vector for gene delivery has been shown to exhibit enhanced delivery and bioavailability while offering a heightened safety profile. Due to topological differ...

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Detalles Bibliográficos
Autores principales: Sum, Chi Hong, Nafissi, Nafiseh, Slavcev, Roderick A., Wettig, Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642985/
https://www.ncbi.nlm.nih.gov/pubmed/26561857
http://dx.doi.org/10.1371/journal.pone.0142875