Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses

Several pathogens have been described to enter host cells via cholesterol-enriched membrane lipid raft microdomains. We found that disruption of lipid rafts by the cholesterol-extracting agent methyl-β-cyclodextrin or by the cholesterol-binding antifungal drug Amphotericin B strongly impairs the upt...

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Detalles Bibliográficos
Autores principales: de Turris, Valeria, Teloni, Raffaela, Chiani, Paola, Bromuro, Carla, Mariotti, Sabrina, Pardini, Manuela, Nisini, Roberto, Torosantucci, Antonella, Gagliardi, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643028/
https://www.ncbi.nlm.nih.gov/pubmed/26562838
http://dx.doi.org/10.1371/journal.pone.0142531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643028/
https://www.ncbi.nlm.nih.gov/pubmed/26562838
http://dx.doi.org/10.1371/journal.pone.0142531

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