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Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease with poorly understood etiology and pathobiology. Mitogen activated protein kinases (MAPKs) including ERK and p38 play important roles in the mediation of downstream pathways involved in cartilage degenerative processes. Dual specificit...

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Detalles Bibliográficos
Autores principales: Pest, Michael Andrew, Pest, Courtney Alice, Bellini, Melina Rodrigues, Feng, Qingping, Beier, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643037/
https://www.ncbi.nlm.nih.gov/pubmed/26562438
http://dx.doi.org/10.1371/journal.pone.0142822