Mutational Hotspot of TET2, IDH1, IDH2, SRSF2, SF3B1, KRAS, and NRAS from Human Systemic Mastocytosis Are Not Conserved in Canine Mast Cell Tumors

INTRODUCTION: Both canine cutaneous mast cell tumor (MCT) and human systemic mastocytosis (SM) are characterized by abnormal proliferation and accumulation of mast cells in tissues and, frequently, by the presence of activating mutations in the receptor tyrosine kinase V-Kit Hardy-Zuckerman 4 Feline...

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Detalles Bibliográficos
Autores principales: Zorzan, Eleonora, Hanssens, Katia, Giantin, Mery, Dacasto, Mauro, Dubreuil, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643045/
https://www.ncbi.nlm.nih.gov/pubmed/26562302
http://dx.doi.org/10.1371/journal.pone.0142450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643045/
https://www.ncbi.nlm.nih.gov/pubmed/26562302
http://dx.doi.org/10.1371/journal.pone.0142450

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