Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors through MAPK Signaling Pathways in MC3T3-E1 cells

Objective: Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We focused on the degradation p...

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Detalles Bibliográficos
Autores principales: Karasawa, Yoko, Tanaka, Hideki, Nakai, Kumiko, Tanabe, Natsuko, Kawato, Takayuki, Maeno, Masao, Shimizu, Noriyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643081/
https://www.ncbi.nlm.nih.gov/pubmed/26640410
http://dx.doi.org/10.7150/ijms.13263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643081/
https://www.ncbi.nlm.nih.gov/pubmed/26640410
http://dx.doi.org/10.7150/ijms.13263

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