Cargando…

Tension Force Downregulates Matrix Metalloproteinase Expression and Upregulates the Expression of Their Inhibitors through MAPK Signaling Pathways in MC3T3-E1 cells

Objective: Matrix metalloproteinases (MMPs), produced by osteoblasts, catalyze the turnover of extracellular matrix (ECM) molecules in osteoid, and the regulation of MMP activity depends on interactions between MMPs and tissue inhibitors of metalloproteinases (TIMPs). We focused on the degradation p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karasawa, Yoko, Tanaka, Hideki, Nakai, Kumiko, Tanabe, Natsuko, Kawato, Takayuki, Maeno, Masao, Shimizu, Noriyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643081/ https://www.ncbi.nlm.nih.gov/pubmed/26640410 http://dx.doi.org/10.7150/ijms.13263

Ejemplares similares

Effects of C-reactive protein on the expression of matrix metalloproteinases and their inhibitors via Fcγ receptors on 3T3-L1 adipocytes
por: Nakai, Kumiko, et al.
Publicado: (2017)

Tension Force-Induced ATP Promotes Osteogenesis Through P2X7 Receptor in Osteoblasts
por: Kariya, Taro, et al.
Publicado: (2015)

Nicotine Affects Bone Resorption and Suppresses the Expression of Cathepsin K, MMP-9 and Vacuolar-Type H(+)-ATPase d2 and Actin Organization in Osteoclasts
por: Tanaka, Hideki, et al.
Publicado: (2013)

Effect of Azithromycin on Mineralized Nodule Formation in MC3T3-E1 Cells
por: Kato, Kengo, et al.
Publicado: (2021)

Continuous Compressive Force Induces Differentiation of Osteoclasts with High Levels of Inorganic Dissolution
por: Matsuike, Rieko, et al.
Publicado: (2019)

Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLCγ1/JNK/NF-κB Pathway in MC3T3-E1 Cells
por: Tanabe, Natsuko, et al.
Publicado: (2023)

Angiotensin II suppresses osteoblastic differentiation and mineralized nodule formation via AT(1) receptor in ROS17/2.8 cells
por: Nakai, Kumiko, et al.
Publicado: (2015)

Curcumin Inhibits Proliferation of Synovial Cells by Downregulating Expression of Matrix Metalloproteinase‐3 in Osteoarthritis
por: Zeng, Jian‐jun, et al.
Publicado: (2018)

Effect of Periodontitis and Toothbrushing Frequency on Obesity Onset: A Cohort Study
por: Morita, Toyoko, et al.
Publicado: (2019)

Effects of Electric-Toothbrush Vibrations on the Expression of Collagen and Non-Collagen Proteins through the Focal Adhesion Kinase Signaling Pathway in Gingival Fibroblasts
por: Nakai, Kumiko, et al.
Publicado: (2022)

Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours
por: BUGAEVA, Olga, et al.
Publicado: (2023)

Phosphorylation of FOXP3 by LCK Downregulates MMP9 Expression and Represses Cell Invasion
por: Nakahira, Kumiko, et al.
Publicado: (2013)

Expression of matrix metalloproteinase‐3 and ‐10 is up‐regulated in the periodontal tissues of aged mice
por: Kageyama, Yoko, et al.
Publicado: (2022)

Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes
por: Liacini, Abdelhamid, et al.
Publicado: (2005)

MicroRNA-216a-3p promotes sorafenib sensitivity in hepatocellular carcinoma by downregulating MAPK14 expression
por: Wan, Zhong, et al.
Publicado: (2020)

The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways
por: Lee, Hee Jeong, et al.
Publicado: (2018)

EGCG, GCG, TFDG, or TSA Inhibiting Melanin Synthesis by Downregulating MC1R Expression
por: Wang, Wei, et al.
Publicado: (2023)

Sesame lignans upregulate glutathione S-transferase expression and downregulate microRNA-669c-3p
por: MARUGAME, Yuki, et al.
Publicado: (2022)

Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes
por: Chen, Wei-Ping, et al.
Publicado: (2015)

MC Sensor—A Novel Method for Measurement of Muscle Tension
por: Đorđević, Srđan, et al.
Publicado: (2011)

Vinculin expression in MC3T3-E1 cells in response to mechanical stimulus
por: Cora-Cruz, J.J., et al.
Publicado: (2015)

Gene Expression in MC3T3-E1 Cells Treated with Diclofenac and Methylprednisolone
por: Lehmann, Tomasz P., et al.
Publicado: (2023)

Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression
por: MA, JUNJI, et al.
Publicado: (2015)

118 EGCG Downregulates Mucin Gene Expression Through the Mapk Signaling Pathway in Asthma
por: Kim, Yong-Dae, et al.
Publicado: (2012)

Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9
por: CHEN, SHAO-JUN, et al.
Publicado: (2016)

Influence of Heating and Cyclic Tension on the Induction of Heat Shock Proteins and Bone-Related Proteins by MC3T3-E1 Cells
por: Chung, Eunna, et al.
Publicado: (2014)

LBODP080 Mc3r Expression In Liver Tissue Is Partially Responsible For The Severity Of Murine MC3R Deficiency Associated Obesity
por: Jain, Arad, et al.
Publicado: (2022)

Downregulation of microRNA-9 increases matrix metalloproteinase-13 expression levels and facilitates osteoarthritis onset
por: Zhang, Hongxin, et al.
Publicado: (2018)

Gene expression of MC3T3-E1 osteoblastic cells on titanium and zirconia surface
por: Gong, Soon-Hyun, et al.
Publicado: (2013)

Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
por: Kang, Dong-Geun, et al.
Publicado: (2017)

Expression of collagenases (matrix metalloproteinase-1, -8, -13) and tissue inhibitor of metalloproteinase-3 (TIMP-3) in naturally occurring bovine cutaneous fibropapillomas
por: Daraban Bocaneti, Florentina, et al.
Publicado: (2023)

EMMPRIN Inhibits bFGF-Induced IL-6 Secretion in an Osteoblastic Cell Line, MC3T3-E1
por: Saiki, Akari, et al.
Publicado: (2017)

DJ1 expression downregulates in neuroblastoma cells (SK-N-MC) chronically exposed to HIV-1 and cocaine
por: Roy, Upal, et al.
Publicado: (2015)

The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes
por: Elliott, Sarah, et al.
Publicado: (2003)

TNF-α induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-κB activation in osteoblast-like MC3T3-E1 cells
por: Tsai, Chia-Lan, et al.
Publicado: (2014)

KRAS mutation‐independent downregulation of MAPK/PI3K signaling in colorectal cancer
por: Lam, Kuen Kuen, et al.
Publicado: (2022)

MC3T3-E1 Cells on Titanium Surfaces with Nanometer Smoothness and Fibronectin Immobilization
por: Hayakawa, Tohru, et al.
Publicado: (2012)

Glucosamine sulfate suppresses the expression of matrix metalloproteinase-3 in osteosarcoma cells in vitro
por: Pohlig, Florian, et al.
Publicado: (2016)

Regulation of matrix metalloproteinase-3 gene expression in inflammation: A molecular study
por: Teja, Kavalipurapu Venkata, et al.
Publicado: (2018)

Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection
por: Moores, Rachel C., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0ktrfci11kilhq6bv9or72tkdc