PLX4032 Mediated Melanoma Associated Antigen Potentiation in Patient Derived Primary Melanoma Cells

Over expression of various immunogenic melanoma associated antigens (MAAs) has been exploited in the development of immunotherapeutic melanoma vaccines. Expression of MAAs such as MART-1 and gp100 is modulated by the MAPK signaling pathway, which is often deregulated in melanoma. The protein BRAF, a...

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Detalles Bibliográficos
Autores principales: George, Andrea L., Suriano, Robert, Rajoria, Shilpi, Osso, Maria C., Tuli, Neha, Hanly, Elyse, Geliebter, Jan, Arnold, Angelo N., Wallack, Marc, Tiwari, Raj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643088/
https://www.ncbi.nlm.nih.gov/pubmed/26640592
http://dx.doi.org/10.7150/jca.11126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643088/
https://www.ncbi.nlm.nih.gov/pubmed/26640592
http://dx.doi.org/10.7150/jca.11126

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