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SF3B1 mutations constitute a novel therapeutic target in breast cancer

Mutations in genes encoding proteins involved in RNA splicing have been found to occur at relatively high frequencies in several tumour types including myelodysplastic syndromes, chronic lymphocytic leukaemia, uveal melanoma, and pancreatic cancer, and at lower frequencies in breast cancer. To inves...

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Detalles Bibliográficos
Autores principales: Maguire, Sarah L, Leonidou, Andri, Wai, Patty, Marchiò, Caterina, Ng, Charlotte KY, Sapino, Anna, Salomon, Anne-Vincent, Reis-Filho, Jorge S, Weigelt, Britta, Natrajan, Rachael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643177/
https://www.ncbi.nlm.nih.gov/pubmed/25424858
http://dx.doi.org/10.1002/path.4483