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Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States

The extent to which Rhodopsin family G-protein-coupled receptors (GPCRs) form invariant oligomers is contentious. Recent single-molecule fluorescence imaging studies mostly argue against the existence of constitutive receptor dimers and instead suggest that GPCRs only dimerize transiently, if at all...

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Detalles Bibliográficos
Autores principales: Latty, Sarah L., Felce, James H., Weimann, Laura, Lee, Steven F., Davis, Simon J., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643199/
https://www.ncbi.nlm.nih.gov/pubmed/26536257
http://dx.doi.org/10.1016/j.bpj.2015.09.004