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TAK1 Regulates Myocardial Response to Pathological Stress via NFAT, NFκB, and Bnip3 Pathways

TAK1 (TGFβ-activated kinase-1) signaling is essential in regulating a number of important biological functions, including innate immunity, inflammatory response, cell growth and differentiation, and myocardial homeostasis. The precise role of TAK1 in the adult heart under pathological conditions rem...

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Detalles Bibliográficos
Autores principales: Li, Lei, Chen, Yi, Li, Jing, Yin, Haifeng, Guo, Xiaoyun, Doan, Jessica, Molkentin, Jeffery D., Liu, Qinghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643217/
https://www.ncbi.nlm.nih.gov/pubmed/26564789
http://dx.doi.org/10.1038/srep16626