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A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression

Pathological modification of α-synuclein is believed to be an important event in pathogenesis of Parkinson’s disease and several other neurodegenerative diseases. In normal cells this protein has been linked to many intracellular processes and pathways. However, neither normal function of α-synuclei...

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Detalles Bibliográficos
Autores principales: Ninkina, Natalia, Connor-Robson, Natalie, Ustyugov, Alexey A., Tarasova, Tatiana V., Shelkovnikova, Tatyana A., Buchman, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643252/
https://www.ncbi.nlm.nih.gov/pubmed/26564109
http://dx.doi.org/10.1038/srep16615