Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions

Polarization of cells into a protrusive front and a retracting cell body is the hallmark of mesenchymal-like cell migration. Many mRNAs are localized to protrusions, but it is unclear to what degree mRNA localization contributes toward protrusion formation. We performed global quantitative analysis...

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Detalles Bibliográficos
Autores principales: Mardakheh, Faraz K., Paul, Angela, Kümper, Sandra, Sadok, Amine, Paterson, Hugh, Mccarthy, Afshan, Yuan, Yinyin, Marshall, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643311/
https://www.ncbi.nlm.nih.gov/pubmed/26555054
http://dx.doi.org/10.1016/j.devcel.2015.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643311/
https://www.ncbi.nlm.nih.gov/pubmed/26555054
http://dx.doi.org/10.1016/j.devcel.2015.10.005

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