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Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions
Polarization of cells into a protrusive front and a retracting cell body is the hallmark of mesenchymal-like cell migration. Many mRNAs are localized to protrusions, but it is unclear to what degree mRNA localization contributes toward protrusion formation. We performed global quantitative analysis...
Autores principales: | Mardakheh, Faraz K., Paul, Angela, Kümper, Sandra, Sadok, Amine, Paterson, Hugh, Mccarthy, Afshan, Yuan, Yinyin, Marshall, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643311/ https://www.ncbi.nlm.nih.gov/pubmed/26555054 http://dx.doi.org/10.1016/j.devcel.2015.10.005 |
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