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Sporadic diffuse segmental interstitial cell of Cajal hyperplasia harbouring two gastric gastrointestinal stromal tumours (GIST) mimicking hereditary GIST syndromes

INTRODUCTION: Gastrointestinal stromal tumours (GISTs) are thought to derive from or differentiate towards the interstitial cells of Cajal (ICC) as most demonstrate a similar immunoprofile: CD117+, CD34+ and DOG1+. ICC hyperplasia refers to KIT-expressing microscopic spindle cell proliferations invo...

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Detalles Bibliográficos
Autores principales: Neves, Mafalda Costa, Stamp, Gordon, Mudan, Satvinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643472/
https://www.ncbi.nlm.nih.gov/pubmed/26521201
http://dx.doi.org/10.1016/j.ijscr.2015.10.006