Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis

BACKGROUND: Early death during TB treatment is associated with depressed TNFα response to antigenic stimulation and propensity to superadded bacterial infection. Hypothesising the role of monocyte unresponsiveness, we further compared the immunological profile between patients who died or suffered a...

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Detalles Bibliográficos
Autores principales: Waitt, Catriona John, Banda, Peter, Glennie, Sarah, Kampmann, Beate, Squire, S. Bertel, Pirmohamed, Munir, Heyderman, Robert Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643523/
https://www.ncbi.nlm.nih.gov/pubmed/26567164
http://dx.doi.org/10.1186/s12879-015-1274-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643523/
https://www.ncbi.nlm.nih.gov/pubmed/26567164
http://dx.doi.org/10.1186/s12879-015-1274-4

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