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Rich RNA Structure Landscapes Revealed by Mutate-and-Map Analysis

Landscapes exhibiting multiple secondary structures arise in natural RNA molecules that modulate gene expression, protein synthesis, and viral. We report herein that high-throughput chemical experiments can isolate an RNA’s multiple alternative secondary structures as they are stabilized by systemat...

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Detalles Bibliográficos
Autores principales: Cordero, Pablo, Das, Rhiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643908/
https://www.ncbi.nlm.nih.gov/pubmed/26566145
http://dx.doi.org/10.1371/journal.pcbi.1004473