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Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways

Activation of the dorsomedial nucleus of the hypothalamus (DMH) by galanin (GAL) induces behavioural hyperalgesia. Since DMH neurones do not project directly to the spinal cord, we hypothesized that the medullary dorsal reticular nucleus (DRt), a pronociceptive region projecting to the spinal dorsal...

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Detalles Bibliográficos
Autores principales: Amorim, Diana, Viisanen, Hanna, Wei, Hong, Almeida, Armando, Pertovaara, Antti, Pinto-Ribeiro, Filipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643915/
https://www.ncbi.nlm.nih.gov/pubmed/26565961
http://dx.doi.org/10.1371/journal.pone.0142919