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Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections

Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the same, but not the other serotypes. The specif...

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Detalles Bibliográficos
Autores principales: Rockstroh, Alexandra, Barzon, Luisa, Pacenti, Monia, Palù, Giorgio, Niedrig, Matthias, Ulbert, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643925/
https://www.ncbi.nlm.nih.gov/pubmed/26565964
http://dx.doi.org/10.1371/journal.pntd.0004218