Bringing Down Cancer Aircraft: Searching for Essential Hypomutated Proteins in Skin Melanoma

We propose an approach to detection of essential genes/proteins required for cancer cell survival. A gene is considered essential if a mutation with high impact upon the function of encoded protein causes death of the cancer cell. We draw an analogy between essential cancer proteins and well-known A...

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Detalles Bibliográficos
Autores principales: Pyatnitskiy, Mikhail, Karpov, Dmitriy, Poverennaya, Ekaterina, Lisitsa, Andrey, Moshkovskii, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643971/
https://www.ncbi.nlm.nih.gov/pubmed/26565620
http://dx.doi.org/10.1371/journal.pone.0142819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643971/
https://www.ncbi.nlm.nih.gov/pubmed/26565620
http://dx.doi.org/10.1371/journal.pone.0142819

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