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Comparative Analysis of Yeast Metabolic Network Models Highlights Progress, Opportunities for Metabolic Reconstruction

We have compared 12 genome-scale models of the Saccharomyces cerevisiae metabolic network published since 2003 to evaluate progress in reconstruction of the yeast metabolic network. We compared the genomic coverage, overlap of annotated metabolites, predictive ability for single gene essentiality wi...

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Detalles Bibliográficos
Autores principales: Heavner, Benjamin D., Price, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643975/
https://www.ncbi.nlm.nih.gov/pubmed/26566239
http://dx.doi.org/10.1371/journal.pcbi.1004530