Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response

Anti-apoptotic protein Lifeguard (LFG) is upregulated on T cells upon in vitro activation. To investigate its role in T cell immunity we infected wild type and LFG knockout bone marrow chimaeras mice with LCMV. We observed a decreased number of LFG KO activated CD8 and CD4 T cells throughout the inf...

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Detalles Bibliográficos
Autores principales: Hurtado de Mendoza, Tatiana, Liu, Fei, Verma, Inder M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643990/
https://www.ncbi.nlm.nih.gov/pubmed/26565411
http://dx.doi.org/10.1371/journal.pone.0142161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643990/
https://www.ncbi.nlm.nih.gov/pubmed/26565411
http://dx.doi.org/10.1371/journal.pone.0142161

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