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Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice

OBJECTIVE: An experimental model of endocardial thrombosis has not been developed and endocardial endothelial dysfunction in heart failure (HF) is understudied. We sought to determine whether disruption of the endothelial anti-coagulant activated protein C (APC) pathway in CREB(A133) HF mice promote...

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Detalles Bibliográficos
Autores principales: Schoner, Amanda, Tyrrell, Christina, Wu, Melinda, Gelow, Jill M., Hayes, Alicia A., Lindner, Jonathan R., Thornburg, Kent L., Hasan, Wohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643996/
https://www.ncbi.nlm.nih.gov/pubmed/26565707
http://dx.doi.org/10.1371/journal.pone.0142940