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Endocardial Endothelial Dysfunction Progressively Disrupts Initially Anti then Pro-Thrombotic Pathways in Heart Failure Mice
OBJECTIVE: An experimental model of endocardial thrombosis has not been developed and endocardial endothelial dysfunction in heart failure (HF) is understudied. We sought to determine whether disruption of the endothelial anti-coagulant activated protein C (APC) pathway in CREB(A133) HF mice promote...
Autores principales: | Schoner, Amanda, Tyrrell, Christina, Wu, Melinda, Gelow, Jill M., Hayes, Alicia A., Lindner, Jonathan R., Thornburg, Kent L., Hasan, Wohaib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643996/ https://www.ncbi.nlm.nih.gov/pubmed/26565707 http://dx.doi.org/10.1371/journal.pone.0142940 |
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