Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster

The Adaptor Protein (AP)-3 complex is an evolutionary conserved, molecular sorting device that mediates the intracellular trafficking of proteins to lysosomes and related organelles. Genetic defects in AP-3 subunits lead to impaired biogenesis of lysosome-related organelles (LROs) such as mammalian...

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Detalles Bibliográficos
Autores principales: Rodriguez-Fernandez, Imilce A., Dell’Angelica, Esteban C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643998/
https://www.ncbi.nlm.nih.gov/pubmed/26565960
http://dx.doi.org/10.1371/journal.pone.0143026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643998/
https://www.ncbi.nlm.nih.gov/pubmed/26565960
http://dx.doi.org/10.1371/journal.pone.0143026

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