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In silico evaluation of gadofosveset pharmacokinetics in different population groups using the Simcyp® simulator platform

PURPOSE: Gadofosveset is a Gd-based contrast agent used for magnetic resonance imaging (MRI). Gadolinium kinetic distribution models are implemented in T1-weighted dynamic contrast-enhanced perfusion MRI for characterization of lesion sites in the body. Physiology changes in a disease state potentia...

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Detalles Bibliográficos
Autores principales: Spanakis, Marios, Marias, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644137/
https://www.ncbi.nlm.nih.gov/pubmed/27502621
http://dx.doi.org/10.1186/s40203-014-0002-x