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In silico evaluation of gadofosveset pharmacokinetics in different population groups using the Simcyp® simulator platform
PURPOSE: Gadofosveset is a Gd-based contrast agent used for magnetic resonance imaging (MRI). Gadolinium kinetic distribution models are implemented in T1-weighted dynamic contrast-enhanced perfusion MRI for characterization of lesion sites in the body. Physiology changes in a disease state potentia...
Autores principales: | Spanakis, Marios, Marias, Kostas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644137/ https://www.ncbi.nlm.nih.gov/pubmed/27502621 http://dx.doi.org/10.1186/s40203-014-0002-x |
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