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Mathematical analysis of the sodium sensitivity of the human histamine H(3) receptor
PURPOSE: It was shown by several experimental studies that some G protein coupled receptors (GPCR) are sensitive to sodium ions. Furthermore, mutagenesis studies or the determination of crystal structures of the adenosine A(2A) or δ-opioid receptor revealed an allosteric Na(+) binding pocket near to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644138/ https://www.ncbi.nlm.nih.gov/pubmed/27502620 http://dx.doi.org/10.1186/s40203-014-0001-y |