Mathematical analysis of the sodium sensitivity of the human histamine H(3) receptor

PURPOSE: It was shown by several experimental studies that some G protein coupled receptors (GPCR) are sensitive to sodium ions. Furthermore, mutagenesis studies or the determination of crystal structures of the adenosine A(2A) or δ-opioid receptor revealed an allosteric Na(+) binding pocket near to...

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Detalles Bibliográficos
Autores principales: Wittmann, Hans-Joachim, Seifert, Roland, Strasser, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644138/
https://www.ncbi.nlm.nih.gov/pubmed/27502620
http://dx.doi.org/10.1186/s40203-014-0001-y

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