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Transcriptomic Heterogeneity in Cancer as a Consequence of Dysregulation of the Gene–Gene Interaction Network
Many pathways are dysregulated in cancer. Dysregulation of the regulatory network results in less control of transcript levels in the cell. Hence, dysregulation is reflected in the heterogeneity of the transcriptome: the more dysregulated the pathway, the more the transcriptomic heterogeneity. We id...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644214/ https://www.ncbi.nlm.nih.gov/pubmed/26376888 http://dx.doi.org/10.1007/s11538-015-0103-7 |