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Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation
ESCRT-III is required for lipid membrane remodeling in many cellular processes, from abscission to viral budding and multi-vesicular body biogenesis. However, how ESCRT-III polymerization generates membrane curvature remains debated. Here, we show that Snf7, the main component of ESCRT-III, polymeri...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644223/ https://www.ncbi.nlm.nih.gov/pubmed/26522593 http://dx.doi.org/10.1016/j.cell.2015.10.017 |