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A subset of CD163(+) macrophages displays mixed polarizations in discoid lupus skin

INTRODUCTION: Lesional skin of patients with discoid lupus erythematosus (DLE) contains macrophages, whose polarization has yet to be investigated. To test our hypothesis that M1 macrophages would be increased in DLE skin, we examined transcriptome alterations in immune cell gene expression and macr...

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Detalles Bibliográficos
Autores principales: Chong, Benjamin F., Tseng, Lin-chiang, Hosler, Gregory A., Teske, Noelle M., Zhang, Song, Karp, David R., Olsen, Nancy J., Mohan, Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644297/
https://www.ncbi.nlm.nih.gov/pubmed/26568320
http://dx.doi.org/10.1186/s13075-015-0839-3